Treatment with metformin prevents pre-eclampsia by suppressing migration of trophoblast cells via modulating the signaling pathway of UCA1/miR-204/MMP-9.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.099
Abstract: Metformin has been reported to be involved in the pathogenesis of PE (pre-eclampsia). This study aims to investigate the molecular mechanism of how UCA1 interferes with MMP9 expression under the influence of metformin, which contributes… read more here.
Keywords: uca1 mir; metformin; pre eclampsia; migration ... See more keywords
Correlation between expression levels of lncRNA UCA1 and miR-18a with prognosis of hepatocellular cancer.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202004_20820
Abstract: OBJECTIVE To uncover the prognostic potentials of long non-coding RNA (lncRNA) UCA1 and miR-18a in hepatocellular cancer (HCC). PATIENTS AND METHODS Expression levels of UCA1 and microRNA-18a (miR-18a) in HCC tissues and adjacent normal ones… read more here.
Keywords: uca1 mir; mir 18a; hcc patients; level ... See more keywords
Plasma Lnc-UCA1/miR-138 axis as a potential biomarker for gestational diabetes mellitus and neonatal prognosis.
Sign Up to like & getrecommendations! Published in 2022 at "Ginekologia polska"
DOI: 10.5603/gp.a2022.0052
Abstract: OBJECTIVES This study aimed to explore the correlations of Lnc-UCA1/miR-138 axis with gestational diabetes mellitus (GDM) risk and neonatal prognosis. MATERIAL AND METHODS First, the blood samples from sixty GDM patients and 60 healthy pregnant… read more here.
Keywords: lnc uca1; mir 138; uca1 mir; 138 axis ... See more keywords