Analysis of Selenoprotein F Binding to UDP‐Glucose:Glycoprotein Glucosyltransferase (UGGT) by a Photoreactive Crosslinker
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200444
Abstract: In the endoplasmic reticulum glycoprotein quality control system, UDP‐glucose : glycoprotein glucosyltransferase (UGGT) functions as a folding sensor. Although it is known to form a heterodimer with selenoprotein F (SelenoF), the details of the complex… read more here.
Keywords: selenof; glycoprotein glucosyltransferase; glucose glycoprotein; udp glucose ... See more keywords
Arabidopsis MAP-Kinase 3 Phosphorylates UDP-Glucose Dehydrogenase: a Key Enzyme Providing UDP-Sugar for Cell Wall Biosynthesis
Sign Up to like & getrecommendations! Published in 2018 at "Plant Molecular Biology Reporter"
DOI: 10.1007/s11105-018-1130-y
Abstract: The enzyme UDP-glucose dehydrogenase (UGD) competes with sucrose-phosphate synthase for the common photosynthesis product UDP-glucose. Sucrose-phosphate synthase is part of a pathway for the export of sucrose from source leaves to neighboring cells or the… read more here.
Keywords: wall biosynthesis; udp glucose; cell wall;
UDP-glucose pyrophosphorylase gene affects mycelia growth and polysaccharide synthesis of Grifola frondosa.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.06.139
Abstract: To elucidate potential roles of UDP-glucose pyrophosphorylase (UGP) in mycelial growth and polysaccharide synthesis of Grifola frondosa, a putative 2036-bp UDP-glucose pyrophosphorylase gene gfugp encoding a 53.17-kDa protein was cloned and re-annotated. Two dual promoter… read more here.
Keywords: udp glucose; glucose pyrophosphorylase; polysaccharide synthesis; growth polysaccharide ... See more keywords
UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.09.061
Abstract: INTRODUCTION P2Y14, one of the P2Y purinergic G-protein coupled receptors, is expressed in a variety of cells and tissues. Its ligand, UDP-glucose (UDPG), is released from damaged and stress-stimulated cells and acts as a danger… read more here.
Keywords: enhance invasion; extravillous trophoblast; p2y14; invasion ... See more keywords
Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00497
Abstract: Human UDP-glucose dehydrogenase (hUGDH) oxidizes UDP-glucose to UDP-glucuronic acid, an essential substrate in the phase II metabolism of drugs. The activity of hUGDH is regulated by the conformation of a buried allosteric switch (T131 loop/α6… read more here.
Keywords: state; udp glucose; hysteresis; protein core ... See more keywords
Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration
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DOI: 10.1038/s41388-018-0138-y
Abstract: UDP-glucose 6-dehydrogenase (UGDH) produces UDP-α-d-glucuronic acid, the precursors for glycosaminoglycans (GAGs) and proteoglycans of the extracellular matrix. Elevated GAG formation has been implicated in a variety of human diseases, including glioblastoma (GBM). In our previous… read more here.
Keywords: udp glucose; migration; growth migration; glucose dehydrogenase ... See more keywords
cDNA isolation and functional characterization of UDP-glucose 4-epimerase from Davallia divaricate
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2019.1703697
Abstract: Abstract UDP-glucose 4-epimerase (UGE) is a universal enzyme responsible for interconversion of UDP-glucose and UDP-galactose. However, the gene encoding UGE from Davallia divaricate is elusive. In this study, two UGE genes, ddUGE1 and ddUGE2, were… read more here.
Keywords: davallia divaricate; udp glucose; divaricate; glucose epimerase ... See more keywords
Acinetobacter baumannii K20 and K21 capsular polysaccharide structures establish roles for UDP-glucose dehydrogenase Ugd2, pyruvyl transferase Ptr2 and two glycosyltransferases
Sign Up to like & getrecommendations! Published in 2018 at "Glycobiology"
DOI: 10.1093/glycob/cwy074
Abstract: Infections caused by Acinetobacter baumannii isolates from the major global clones, GC1 and GC2, are difficult to treat with antibiotics, and phage therapy, which requires extensive knowledge of the variation in the surface polysaccharides, is… read more here.
Keywords: glucose dehydrogenase; udp glucose; capsular polysaccharide; k20 k21 ... See more keywords
The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4084-4
Abstract: The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. Interestingly, the UGCG is also… read more here.
Keywords: protein; udp glucose; resistance; glucose ceramide ... See more keywords
UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism
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DOI: 10.1371/journal.pone.0274420
Abstract: UDP-glucose dehydrogenase (UGDH) generates essential precursors of hyaluronic acid (HA) synthesis, however mechanisms regulating its activity are unclear. We used enzyme histostaining and quantitative image analysis to test whether cytokines that stimulate HA synthesis upregulate… read more here.
Keywords: ugdh activity; udp glucose; diaphorase; dehydrogenase ugdh ... See more keywords
Role of UDP-glucose ceramide glucosyltransferase in venous malformation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1178045
Abstract: Venous malformation (VM) results from the abnormal growth of the vasculature; however, the detailed molecular mechanism remains unclear. As a glycosyltransferase, UDP-glucose ceramide glucosyltransferase (UGCG) is localized to the Golgi body and is a key… read more here.
Keywords: ceramide glucosyltransferase; glucose ceramide; udp glucose; venous malformation ... See more keywords