Polypeptoids synthesis based on Ugi reaction: Advances and perspectives
Sign Up to like & getrecommendations! Published in 2019 at "Biopolymers"
DOI: 10.1002/bip.23288
Abstract: Polypeptoids are peptidomimetic polymers invented in the early 1990s. Although polypeptoid chemistry is developing rapidly, the simple synthesis of polypeptoids and sequence‐controlled polypeptoids still remains a challenge. Fortunately, we have seen a drastic rising trend… read more here.
Keywords: synthesis based; ugi reaction; chemistry; polypeptoids synthesis ... See more keywords
Ugi Reaction of Amino Acids: From Facile Synthesis of Polypeptoids to Sequence-Defined Macromolecules.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202000515
Abstract: Polypeptoids have been prepared and researched for more than 20 years. However, the efficient generation of polypeptoids and sequence-defined polypeptoids faces many challenges and difficulties. The Ugi reaction of amino acids has recently been introduced… read more here.
Keywords: sequence defined; reaction amino; ugi reaction; amino acids ... See more keywords
SuFExable Isocyanides for Ugi Reaction: Synthesis of Sulfonyl Fluoro Peptides.
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DOI: 10.1021/acs.orglett.1c01734
Abstract: Herein, the sulfonyl fluoro isocyanides were first developed as a new type of SuFExable synthon, and they are used as building blocks in the Ugi reaction (U-4CR). The Ugi reaction was established and the substrate… read more here.
Keywords: fluoro peptides; ugi reaction; sulfonyl fluoro; synthesis ... See more keywords
Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
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DOI: 10.1021/acsomega.0c00369
Abstract: This study describes the solvent and catalyst-free Ugi reaction by way of twin screw extrusion (TSE). Multicomponent chemical synthesis can be converted into a single process without repeated use of solvents through TSE. High synthetic… read more here.
Keywords: solvent catalyst; twin screw; screw extrusion; ugi reaction ... See more keywords