Polypeptoids synthesis based on Ugi reaction: Advances and perspectives
Sign Up to like & getrecommendations! Published in 2019 at "Biopolymers"
DOI: 10.1002/bip.23288
Abstract: Polypeptoids are peptidomimetic polymers invented in the early 1990s. Although polypeptoid chemistry is developing rapidly, the simple synthesis of polypeptoids and sequence‐controlled polypeptoids still remains a challenge. Fortunately, we have seen a drastic rising trend… read more here.
Keywords: synthesis based; ugi reaction; chemistry; polypeptoids synthesis ... See more keywords
Ugi Reaction of Amino Acids: From Facile Synthesis of Polypeptoids to Sequence-Defined Macromolecules.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202000515
Abstract: Polypeptoids have been prepared and researched for more than 20 years. However, the efficient generation of polypeptoids and sequence-defined polypeptoids faces many challenges and difficulties. The Ugi reaction of amino acids has recently been introduced… read more here.
Keywords: sequence defined; reaction amino; ugi reaction; amino acids ... See more keywords
SuFExable Isocyanides for Ugi Reaction: Synthesis of Sulfonyl Fluoro Peptides.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01734
Abstract: Herein, the sulfonyl fluoro isocyanides were first developed as a new type of SuFExable synthon, and they are used as building blocks in the Ugi reaction (U-4CR). The Ugi reaction was established and the substrate… read more here.
Keywords: fluoro peptides; ugi reaction; sulfonyl fluoro; synthesis ... See more keywords
Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
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DOI: 10.1021/acsomega.0c00369
Abstract: This study describes the solvent and catalyst-free Ugi reaction by way of twin screw extrusion (TSE). Multicomponent chemical synthesis can be converted into a single process without repeated use of solvents through TSE. High synthetic… read more here.
Keywords: solvent catalyst; twin screw; screw extrusion; ugi reaction ... See more keywords
Eudragit® L100 Post-Modification via Ugi Multicomponent Reaction
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Brazilian Chemical Society"
DOI: 10.21577/0103-5053.20240061
Abstract: This work investigated the post-modification of commercial poly(methyl mechacrylate-coacrylic acid) using the versatile multicomponent Ugi reaction. This reaction introduces diverse functionalities to tailor the polymer properties effectively. The commercial copolymer which is known for biocompatibility… read more here.
Keywords: reaction; post modification; eudragit l100; ugi reaction ... See more keywords