Impact of UGT1A1 polymorphisms on Raltegravir and its glucuronide plasma concentrations in a cohort of HIV-1 infected patients
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DOI: 10.1038/s41598-018-25803-z
Abstract: The aim of this study was to evaluate the effect of UGT1A1 polymorphisms on Raltegravir (RAL) and its metabolite RAL-glucuronide trough plasma concentrations ([RAL]plasma and [RAL-glu]plasma) and on the metabolic ratio (MR): [RAL-glu]plasma/[RAL]plasma. UGT1A1 genotyping… read more here.
Keywords: polymorphisms raltegravir; plasma concentrations; ugt1a1 polymorphisms; ugt1a1 ugt1a1 ... See more keywords