Impact of clinical factors and UGT1A9 and CYP2B6 genotype on inter-individual differences in propofol pharmacokinetics
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2470-3
Abstract: PurposePropofol is one of the most widely used fast-acting intravenously administered anesthetics. However, although large inter-individual differences in dose requirements and recovery time have been observed, there are few previous studies in which the association… read more here.
Keywords: individual differences; analysis; clinical factors; propofol pharmacokinetics ... See more keywords
The Effect of UGT1A9, CYP2B6 and CYP2C9 Genes Polymorphism on Propofol Pharmacokinetics in Children
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s231329
Abstract: Purpose This study was conducted to determine the effect of UGT1A9 98T>C, CYP2B6 516G>T and CYP2C9 430C>T genetic polymorphisms on the pharmacokinetics of propofol in children of different sexes and ages who undergone total intravenous… read more here.
Keywords: propofol; ugt1a9 cyp2b6; polymorphism; cyp2b6 ... See more keywords