UHPLC–MS/MS method for simultaneous quantification of doripenem, meropenem, ciprofloxacin, levofloxacin, pazufloxacin, linezolid, and tedizolid in filtrate during continuous renal replacement therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24815
Abstract: Since severe infections frequently cause acute kidney injury (AKI), continuous renal replacement therapy (CRRT) is often initiated for regulation of inflammatory mediators and renal support. Thus, it is necessary to decide the antibiotic dosage considering… read more here.
Keywords: method simultaneous; replacement therapy; simultaneous quantification; uhplc method ... See more keywords
Development of a UHPLC-MS method for inhibitor screening against α-L-1,3-fucosidase
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-01575-x
Abstract: Abstractα-L-Fucosidase (AFU) is a promising therapeutic target for the treatment of inflammation, cancer, cystic fibrosis, and fucosidosis. Some of the existing analytical methods for the assessment of AFU activity are lacking in sensitivity and selectivity,… read more here.
Keywords: fucosidase; method; inhibitor screening; uhplc method ... See more keywords
UHPLC-MS/MS Method for the Analysis of 2,6 Toluene Diisocyanate and 2,4 Toluene Diisocyanate Released from Microa-gglomerated Corks in Wine
Sign Up to like & getrecommendations! Published in 2020 at "Food Analytical Methods"
DOI: 10.1007/s12161-020-01860-x
Abstract: Micro-agglomerate corks, made by agglutination of cork granulate through the addition of different adhesives, represent an important slice of the market of cork stoppers. Binder glues which are polyurethane- or butadiene-based have been used since… read more here.
Keywords: uhplc method; toluene; toluene diisocyanate; tdi ... See more keywords
A novel, rapid and simple UHPLC-MS/MS method for quantification of warfarin in dried blood spots.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2022.114664
Abstract: Warfarin is a common first line anticoagulant with a narrow therapeutic window. Because of the large blood volume needed, previous warfarin determination methods were not applicable to small animals, such as mice. To reduce the… read more here.
Keywords: rapid simple; simple uhplc; novel rapid; uhplc method ... See more keywords
A UHPLC method for the simultaneous analysis of biogenic amines, amino acids and ammonium ions in beer.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2016.08.040
Abstract: This paper reports a novel UHPLC method for simultaneously quantifying nine biogenic amines, 21 amino acids, and ammonium ions, in beer. Precision values of standard curves slopes were lower than 3.4% and recovery was between… read more here.
Keywords: acids ammonium; amino acids; amines amino; uhplc method ... See more keywords
Determination of the native forms of vitamin B1 in bovine milk using a fast and simplified UHPLC method.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.02.092
Abstract: The aim of this study was to develop a high-throughput UHPLC method for the determination vitamin B1 active compounds; thiamin, thiamin monophosphate and thiamin diphosphate in bovine milk. In order to sustain the native vitamin… read more here.
Keywords: milk; bovine milk; determination; method ... See more keywords
A new UHPLC-MS/MS method for the determination of flavonoids in supplements and DPPH-UHPLC-UV method for the evaluation of the radical scavenging activity of flavonoids.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.02.138
Abstract: The aim of study was to analyze the flavonoid composition of dietary supplements using the UHPLC-MS/MS method and to evaluate the antioxidant activity using the DPPH-UV and DPPH-UHPLC-UV methods. In the first part of the… read more here.
Keywords: antioxidant activity; dpph uhplc; determination; method ... See more keywords
Quantitation of capsaicinoids in different chilies from Austria by a novel UHPLC method
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Food Composition and Analysis"
DOI: 10.1016/j.jfca.2017.03.015
Abstract: Abstract Besides sensorial assays for quantifying pungent components in chilies, nowadays mainly HPLC methods focus on the determination of individual capsaicinoids. Compared to HPLC, ultra-highperformance chromatography (UHPLC) enables shorter runtimes and enhanced resolution. Thus, the… read more here.
Keywords: different chilies; capsaicinoids different; quantitation capsaicinoids; chilies austria ... See more keywords
Determination of higenamine in dietary supplements by UHPLC/MS/MS method
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.08.017
Abstract: HIGHLIGHTSUPLC/HILIC‐/MS/MS method for higenamine quantification was developed and validated.HILIC mode provide adequate retention of higenamine.Method was applied for higenamine determination in selected dietary supplements. ABSTRACT From 1st January 2017 higenamine was added on the WADA… read more here.
Keywords: uhplc method; dietary supplements; higenamine; determination higenamine ... See more keywords
Computer‐assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.11.014
Abstract: HighlightsA generic UHPLC‐MS method development workflow was proposed for the analysis of antineoplastic drugs.Screening, optimization, virtual refinement and virtual robustness testing were done.Limited handling of toxic compounds was required to perform the whole method development.Complete… read more here.
Keywords: method development; method; uhplc method; optimization ... See more keywords
Development and validation of the stability indicating RP-UHPLC method for the determination of the chemical purity and assay of bimatoprost.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.06.002
Abstract: A simple, rapid and accurate ultra-high performance liquid chromatographic (UHPLC) method with a UV detection for the determination of the chemical purity and assay of bimatoprost (BT-1) was developed. The chromatographic separation was achieved with… read more here.
Keywords: determination chemical; validation; purity assay; method ... See more keywords