Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.
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DOI: 10.2210/pdb6fn4/pdb
Abstract: The multidrug transporter ABCB1 (P-glycoprotein) is an ATP-binding cassette transporter that has a key role in protecting tissues from toxic insult and contributes to multidrug extrusion from cancer cells. Here, we report the near-atomic resolution… read more here.
Keywords: zosuquidar uic2; structure zosuquidar; structure; abcb1 ... See more keywords