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Proteomic Signature of Neuroblastoma Cells UKF-NB-4 Reveals Key Role of Lysosomal Sequestration and the Proteasome Complex in Acquiring Chemoresistance to Cisplatin.

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Published in 2019 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.8b00867

Abstract: Cisplatin (CDDP) is a widely used agent in the treatment of neuroblastoma. Unfortunately, the development of acquired chemoresistance limits its clinical use. To gain a detailed understanding of the mechanisms underlying the development of such… read more here.

Keywords: proteasome complex; chemoresistance; cisplatin; neuroblastoma ... See more keywords