Molecular Characterization of Mycobacterium ulcerans DNA Gyrase and Identification of Mutations Reducing Susceptibility to Quinolones In Vitro
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DOI: 10.1128/aac.01902-21
Abstract: Buruli ulcer disease is a neglected necrotizing and disabling cutaneous tropical illness caused by Mycobacterium ulcerans. Fluoroquinolone (FQ), used in the treatment of this disease, has been known to act by inhibiting the enzymatic activities… read more here.
Keywords: disease; mycobacterium ulcerans; ulcerans dna; dna gyrase ... See more keywords