Progression risk factors of ulcerative proctitis
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2022.2094726
Abstract: Abstract Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology. It is characterized by a chronic course with periods of aggravations and remissions. Among patients, 25–55% present with ulcerative proctitis (UP) at the… read more here.
Keywords: disease; progression; risk; course ... See more keywords
DOP64 Endoscopically injected allogeneic mesenchymal stromal cells alter the mucosal immune cell compartment in patients with ulcerative proctitis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab073.103
Abstract: Local mesenchymal stromal cell (MSC)-therapy is approved for the treatment of Crohn’s disease-associated perianal fistulas. However, little is known about the working mechanism of local MSC-therapy. For the first time we evaluated engraftment and immunoregulatory… read more here.
Keywords: therapy; msc therapy; local msc; ulcerative proctitis ... See more keywords
Efficacy of topical 5‐aminosalicylate monotherapy in patients with ulcerative proctitis with skip inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14052
Abstract: In some patients with ulcerative proctitis (UP), skip inflammation is noted in the right side of the colon, but little is known about its clinical course. The aim of this study was to evaluate the… read more here.
Keywords: efficacy topical; ulcerative proctitis; inflammation; skip inflammation ... See more keywords
Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.167402
Abstract: BACKGROUND Due to their immunoregulatory and tissue regenerative features, mesenchymal stromal cells (MSCs) are a promising novel tool for the management of ulcerative proctitis (UP). Here we report on a phase IIa clinical study to… read more here.
Keywords: mesenchymal stromal; local administration; week; immune compartment ... See more keywords
Long-term outcomes of patients with ulcerative proctitis: Analysis from a large referral centre cohort.
Sign Up to like & getrecommendations! Published in 2020 at "United European gastroenterology journal"
DOI: 10.1177/2050640620941345
Abstract: INTRODUCTION Long-term outcomes of patients with ulcerative proctitis (UP) have been poorly investigated, since these patients are excluded from participation in randomized controlled clinical trials. OBJECTIVE The aim of this study was to investigate the… read more here.
Keywords: term; outcomes patients; long term; ulcerative proctitis ... See more keywords