Articles with "ulk complex" as a keyword



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The ULK complex–LRRK1 axis regulates Parkin-mediated mitophagy via Rab7 Ser-72 phosphorylation

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Published in 2022 at "Journal of Cell Science"

DOI: 10.1242/jcs.260395

Abstract: ABSTRACT Mitophagy, a type of selective autophagy, specifically targets damaged mitochondria. The ULK complex regulates Parkin-mediated mitophagy, but the mechanism through which the ULK complex initiates mitophagosome formation remains unknown. The Rab7 GTPase (herein referring… read more here.

Keywords: ser phosphorylation; rab7; ulk complex; mitophagy ... See more keywords