The mammalian ULK1 complex and autophagy initiation
Sign Up to like & getrecommendations! Published in 2017 at "Essays in Biochemistry"
DOI: 10.1042/ebc20170021
Abstract: Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to persist could be detrimental to the… read more here.
Keywords: complex autophagy; autophagy initiation; ulk1; ulk1 complex ... See more keywords
The crucial role of the regulatory mechanism of the Atg1/ULK1 complex in fungi
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1019543
Abstract: Autophagy, an evolutionarily conserved cellular degradation pathway in eukaryotes, is hierarchically regulated by autophagy-related genes (Atgs). The Atg1/ULK1 complex is the most upstream factor involved in autophagy initiation. Here，we summarize the recent studies on the… read more here.
Keywords: mechanism atg1; crucial role; role regulatory; ulk1 complex ... See more keywords