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Ultra-frequent HRAS p.Q61R somatic mutation in canine acanthomatous ameloblastoma reveals pathogenic similarities with human ameloblastoma.

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0 Published in 2019 at "Veterinary and comparative oncology"

DOI: 10.1111/vco.12487

Abstract: Ameloblastoma is a locally aggressive odontogenic tumour that occurs in humans and dogs. Most ameloblastomas (AM) in humans harbour mutually-exclusive driving mutations in BRAF, HRAS, KRAS, NRAS or FGFR2 that activate MAPK signalling, and in… read more here.

Keywords: acanthomatous ameloblastoma; hras q61r; ameloblastoma; ultra frequent ... See more keywords