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Published in 2023 at "Molecular informatics"
DOI: 10.1002/minf.202300026
Abstract: Androgen receptor (AR) inhibition remains the primary strategy to combat the progression of prostate cancer (PC). However, all clinically used AR inhibitors target the ligand-binding domain (LBD), which is highly susceptible to truncations through splicing…
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Keywords:
novel inhibitors;
virtual screening;
androgen receptor;
ultra large ... See more keywords
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Published in 2019 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-019-02071-1
Abstract: Transanal endoscopic microsurgery (TEM) has become the treatment of choice for benign rectal lesions and early rectal cancer (T1). The size classification of rectal polyps is controversial. Some articles define giant rectal lesions as those…
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Keywords:
transanal endoscopic;
large ultra;
large rectal;
ultra large ... See more keywords
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Published in 2019 at "Journal of Energy Storage"
DOI: 10.1016/j.est.2018.12.003
Abstract: Abstract We here report a breakthrough in the fabrication of green high performance symmetric supercapacitors. Our system is based on binder-free reduced graphene oxide foam electrodes using NaCl aqueous electrolyte (1 M). A liquid crystal ultra…
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Keywords:
oxide sheets;
reduced graphene;
graphene oxide;
ultra large ... See more keywords
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Published in 2019 at "Optik"
DOI: 10.1016/j.ijleo.2019.163061
Abstract: Abstract We propose a Sagnac interferometer (SI) based on ethanol-filled photonic crystal fiber (PCF) with two ultra-large holes for temperature measurement. The phase birefringence of the fully-filled PCF varies significantly with the temperature which is…
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Keywords:
large holes;
temperature measurement;
sagnac interferometer;
ethanol ... See more keywords
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Published in 2017 at "Journal of Constructional Steel Research"
DOI: 10.1016/j.jcsr.2016.09.012
Abstract: Abstract The behavior of the beam-to-column joints in steel frames can be represented by the moment-rotation curves in the structural analysis. The moment resistance and the rotational stiffness are two basic parameters in the moment-rotation…
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Keywords:
moment;
moment rotation;
capacity end;
ultra large ... See more keywords
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Published in 2020 at "Materials today communications"
DOI: 10.1016/j.mtcomm.2020.101849
Abstract: Abstract Ultra-large V2O5 xerogel flakes were synthesized by a facile hydrothermal method with commercial V2O5 and H2O2 as raw materials. When evaluated as a cathode material for aqueous Zn-ion batteries in ZnSO4 electrolyte, the ultra-large…
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Keywords:
large v2o5;
ultra large;
v2o5 xerogel;
xerogel flakes ... See more keywords
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Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2117-z
Abstract: On average, an approved drug currently costs US$2–3 billion and takes more than 10 years to develop 1 . In part, this is due to expensive and time-consuming wet-laboratory experiments, poor initial hit compounds and the high…
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Keywords:
virtual screening;
drug;
platform;
ultra large ... See more keywords
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Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr00491g
Abstract: Molybdenum disulfide (MoS2) is a very promising layered material for electrical, optical, and electrochemical applications because of its unique and outstanding properties. To unlock its full potential, among different preparation routes, electrochemistry has gain interest…
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Keywords:
microscopy;
electrochemical thinning;
electrochemistry;
mos2 ... See more keywords
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Published in 2023 at "RSC Advances"
DOI: 10.1039/d3ra00745f
Abstract: Excessive tetracycline in the water environment may lead to the harming of human and ecosystem health. Removing tetracycline antibiotics from aqueous solution is currently a most urgent issue. Porous graphitic biochar with an ultra-large surface…
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Keywords:
ultra large;
surface;
large surface;
graphitic biochar ... See more keywords
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Published in 2023 at "Endoscopy"
DOI: 10.1055/a-2018-4213
Abstract: Aborted peroral endoscopic myotomy (POEM) is rare, and submucosal fibrosis is the most common direct cause of technical failure [1, 2]. Age, disease duration, sigmoid esophagus, and prior interventions are the main risk factors for…
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Keywords:
endoscopic myotomy;
stent;
peroral endoscopic;
ultra large ... See more keywords
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Published in 2023 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2171984
Abstract: ABSTRACT Introduction The size and complexity of virtual screening libraries in drug discovery have skyrocketed in recent years, reaching up to multiple billions of accessible compounds. However, virtual screening of such ultra-large libraries poses several…
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Keywords:
chemotypes ultra;
discovery new;
virtual screening;
ultra large ... See more keywords