High throughput screening of ultrafiltration and diafiltration processing of monoclonal antibodies via the ambr® crossflow system
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DOI: 10.1002/btpr.2929
Abstract: As the biopharmaceutical industry moves toward high concentration of monoclonal antibody drug substance, additional development is required early on when material is still limited. A key constraint is the availability of predictive high‐throughput low‐volume filtration… read more here.
Keywords: system; crossflow system; ambr crossflow; ultrafiltration diafiltration ... See more keywords
Use of ultrafiltration/diafiltration for the processing of antisense oligonucleotides.
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DOI: 10.1002/btpr.3350
Abstract: Ultrafiltration/diafiltration (UF/DF) has been the hallmark for concentrating and buffer exchange of protein and peptide-based therapeutics for years. Here we examine the capabilities and limitations of UF/DF membranes to process oligonucleotides using antisense oligonucleotides (ASOs)… read more here.
Keywords: diafiltration; use ultrafiltration; antisense oligonucleotides; processing antisense ... See more keywords
A Combined Ultrafiltration/Diafiltration Step Facilitates the Purification of Cyanovirin-N From Transgenic Tobacco Extracts
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2018.00206
Abstract: The production of biopharmaceutical proteins in plants offers many advantages over traditional expression platforms, including improved safety, greater scalability and lower upstream production costs. However, most products are retained within plant cells or the apoplastic… read more here.
Keywords: tobacco extracts; step; cyanovirin; ultrafiltration diafiltration ... See more keywords