Ultramicronized N-Palmitoylethanolamine Regulates Mast Cell-Astrocyte Crosstalk: A New Potential Mechanism Underlying the Inhibition of Morphine Tolerance
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DOI: 10.3390/biom13020233
Abstract: Persistent pain can be managed with opioids, but their use is limited by the onset of tolerance. Ultramicronized N-palmitoylethanolamine (PEA) in vivo delays morphine tolerance with mechanisms that are still unclear. Since glial cells are… read more here.
Keywords: morphine tolerance; ultramicronized palmitoylethanolamine; tolerance; pea ... See more keywords