Nucleic Acid Hybridization-Based Noise Suppression for Ultraselective Multiplexed Amplification of Mutant Variants.
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DOI: 10.1002/smll.202006370
Abstract: The analysis of mutant nucleic acid (NA) variants can provide crucial clinical and biological insights for many diseases. Yet, existing analysis techniques are generally constrained by nonspecific "noise" signals from excessive wildtype background sequences, especially… read more here.
Keywords: hybridization; ultraselective multiplexed; mutant variants; hybridization based ... See more keywords