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Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202500523
Abstract: Implant‐associated infections (IAIs) are common and challenging complications of orthopedic surgery. The physical barrier formed by biofilms and the antioxidant defense system of bacteria shield them from attack by antimicrobial agents and immune cells, leading…
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Keywords:
implant associated;
activated selenium;
osseointegration;
associated infections ... See more keywords
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Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-45619-y
Abstract: Implant-associated infections due to the formation of bacterial biofilms pose a serious threat in medical healthcare, which needs effective therapeutic methods. Here, we propose a multifunctional nanoreactor by spatiotemporal ultrasound-driven tandem catalysis to amplify the…
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Keywords:
hot carriers;
activated piezo;
catalysis;
tandem catalysis ... See more keywords
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Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06769a
Abstract: A novel cyanine-rhenium(I) tricarbonyl complex is developed as a potent sonosensitizer and sono-activatable CO-releasing agent for synergistic sonodynamic therapy and CO gas therapy of cancer. The complex induced ferroptosis as the mode of cell death.
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Keywords:
gas;
activated cyanine;
ultrasound activated;
therapy ... See more keywords
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Published in 2025 at "Biomaterials science"
DOI: 10.1039/d5bm00121h
Abstract: Given the global overuse and misuse of antibiotics, the problem of antibiotic resistance has become increasingly severe, necessitating the urgent development of innovative therapeutic strategies to address bacterial infections. In recent years, nanomaterial-mediated sonodynamic therapy…
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Keywords:
generate ros;
antibiotic resistance;
inorganic nanomaterials;
activated inorganic ... See more keywords
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Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2418938122
Abstract: Significance The present work introduces an on-demand cleaning technology that addresses the problem of crystal encrustation and bacterial biofilm formation, with potential applications across various medical devices. Cleaning action is achieved by combining surface topographies…
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Keywords:
cilia biofilm;
activated cilia;
indwelling medical;
medical devices ... See more keywords
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Published in 2021 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2021.2017967
Abstract: Abstract Central nervous system infectious disease caused by the multidrug-resistant Acinetobacter baumannii (AB) seriously threatens human life in clinic. Tigecycline has good sensitivity in killing AB, but due to its wide tissue distribution and blood-brain…
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Keywords:
loaded ultrasound;
antibacterial activity;
preparation;
tigecycline ... See more keywords