An Ultrasound-Responsive Theranostic Cyclodextrin-Loaded Nanoparticle for Multimodal Imaging and Therapy for Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200967
Abstract: Atherosclerosis is a major cause of mortality and morbidity worldwide. Left undiagnosed and untreated, atherosclerotic plaques can rupture and cause cardiovascular complications such as myocardial infarction and stroke. Atherosclerotic plaques are composed of lipids, including… read more here.
Keywords: ultrasound responsive; therapy; multimodal; responsive theranostic ... See more keywords
Tailoring the size of ultrasound responsive lipid-shelled nanodroplets by varying production parameters and environmental conditions
Sign Up to like & getrecommendations! Published in 2021 at "Ultrasonics Sonochemistry"
DOI: 10.1016/j.ultsonch.2021.105482
Abstract: Highlights • Increasing the volumetric concentration of PFP led to an increase in the size of lipid-coated PFP NDs.• Increasing sonication intensity and time led to a decrease in ND size.• The ND coating layer… read more here.
Keywords: size ultrasound; tailoring size; lipid shelled; size ... See more keywords
Pro-apoptotic liposomes-nanobubble conjugate synergistic with paclitaxel: a platform for ultrasound responsive image-guided drug delivery
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21084-8
Abstract: Recently, liposomes-microbubble conjugates have emerged as a promising ultrasound (US)-responsive platform for cancer therapeutics. However, these are limited by their size in terms of tumor penetration. Additionally, there have been no attempts to enhance the… read more here.
Keywords: liposomes nanobubble; pro apoptotic; ultrasound responsive; responsive image ... See more keywords
Dual pH and ultrasound responsive nanoparticles with pH triggered surface charge-conversional properties
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c6py01927g
Abstract: A series of dual pH- and ultrasound responsive statistical copolymers were synthesized via the reversible addition–fragmentation chain transfer (RAFT) polymerization of 3,4-dihydro-2H-pyran (DHP) protected HEMA 2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl methacrylate (THP-HEMA) and 2-(dimethylamino)ethyl methacrylate (DMAEMA). The RAFT-controlled nature… read more here.
Keywords: surface charge; dual ultrasound; microscopy; charge ... See more keywords
Sonophoresis with ultrasound‐responsive liquid‐core nuclei for transdermal drug delivery
Sign Up to like & getrecommendations! Published in 2022 at "Skin Research and Technology"
DOI: 10.1111/srt.13129
Abstract: Sonophoresis can increase the delivery efficiency of various drugs into the skin. A recent advance in sonophoresis is the use of ultrasound‐responsive liquid‐core nuclei (URLN) to increase the probability of cavitation. In this study, we… read more here.
Keywords: core nuclei; liquid core; ultrasound responsive; sonophoresis ... See more keywords
Ultrasound-responsive catalytic microbubbles enhance biofilm elimination and immune activation to treat chronic lung infections.
Sign Up to like & getrecommendations! Published in 2023 at "Science advances"
DOI: 10.1126/sciadv.ade5446
Abstract: Efficient treatment of chronic lung infections caused by Pseudomonas aeruginosa biofilms is a great challenge because of drug tolerance and immune evasion issues. Here, we develop ultrasound-responsive catalytic microbubbles with biofilm elimination and immune activation… read more here.
Keywords: biofilm elimination; ultrasound responsive; chronic lung; lung infections ... See more keywords
pH- and Ultrasound-Responsive Paclitaxel-Loaded Carboxymethyl Chitosan Nanodroplets for Combined Imaging and Synergistic Chemoradiotherapy
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s233669
Abstract: Background Synergistic chemoradiotherapy (CRT) has become a primary effective curative approach for many solid cancers. However, CRT is still associated with several obstacles, including the increases in side effects and systemic toxicity. Incorporating nanocarriers into… read more here.
Keywords: synergistic chemoradiotherapy; loaded nds; ultrasound responsive; combined imaging ... See more keywords
Ultrasound Responsive Smart Implantable Hydrogels for Targeted Delivery of Drugs: Reviewing Current Practices
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s374247
Abstract: Abstract Over the last two decades, the process of delivering therapeutic drugs to a patient with a controlled release profile has been a significant focus of drug delivery research. Scientists have given tremendous attention to… read more here.
Keywords: ultrasound responsive; responsive smart; drug delivery; smart implantable ... See more keywords
Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.956808
Abstract: Bacterial biofilms are a major and ongoing concern for public health, featuring both inherited genetic resistance traits and a conferred innate tolerance to traditional antibiotic therapies. Consequently, there is a growing need for novel methods… read more here.
Keywords: pseudomonas aeruginosa; ultrasound responsive; nitric oxide; ultrasound stimulated ... See more keywords
Ultrasound-Responsive Nanocarriers for Breast Cancer Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13091508
Abstract: Breast cancer is the most common type of cancer and it is treated with surgical intervention, radiotherapy, chemotherapy, or a combination of these regimens. Despite chemotherapy’s ample use, it has limitations such as bioavailability, adverse… read more here.
Keywords: ultrasound responsive; breast cancer; cancer chemotherapy; chemotherapy ... See more keywords
Evading Doxorubicin-Induced Systemic Immunosuppression Using Ultrasound-Responsive Liposomes Combined with Focused Ultrasound
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122603
Abstract: Doxorubicin (DOX) is a representative anticancer drug with a unique ability to induce immunogenic cell death of cancer cells. However, undesired toxicity on immune cells has remained a significant challenge, hindering the usage of DOX… read more here.
Keywords: focused ultrasound; combined therapy; ultrasound responsive; evading doxorubicin ... See more keywords