A More Sustainable Process for Preparation of the Muscarinic Acetylcholine Antagonist Umeclidinium Bromide
Sign Up to like & getrecommendations! Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201800387
Abstract: A more sustainable process for the synthesis of the long‐acting muscarinic acetylcholine antagonist umeclidinium bromide is described. Specifically, we report the synthesis of ethyl 1‐(2‐chloroethyl)‐4‐piperidinecarboxylate, a key intermediate in the preparation of umeclidinium bromide, in… read more here.
Keywords: sustainable process; muscarinic acetylcholine; process; umeclidinium bromide ... See more keywords