Phosphine-Mediated MBH-Type/Umpolung Addition Domino Sequence: Divergent Construction of Coumarins.
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DOI: 10.1021/acs.orglett.9b04248
Abstract: We herein report a phosphine-mediated domino process of MBH-type reaction/umpolung γ-addition through the rational integration of the privileged reactivities of alkynoate. Simply by manipulating the nucleophilic reagent, the developed protocol offers a facile, diversity-oriented construction… read more here.
Keywords: umpolung addition; domino; mbh type; phosphine mediated ... See more keywords