An umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc00046f
Abstract: We have described the first example of an umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition between two aryl aldehydes and a nitrile under the influence of TMSOTf that proceeds through the formation… read more here.
Keywords: strategy intermolecular; intermolecular cycloaddition; trisubstituted oxazoles; umpolung strategy ... See more keywords
An umpolung strategy for chemically selective intermolecular cross-enolate-type coupling of N-alkenoxypyridinium salts with aldehydes.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00422h
Abstract: An efficient method for the synthesis of 1,4-ketoaldehydes via the cross-coupling of N-alkenoxyheteroarenium salts and primary aldehydes is developed. This method provides a broad substrate scope and excellent functional group compatibility. The utility of this… read more here.
Keywords: selective intermolecular; strategy chemically; intermolecular cross; cross ... See more keywords