Palladium-Catalyzed Remote 1,n-Arylamination of Unactivated Terminal Alkenes
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DOI: 10.1021/acscatal.9b00688
Abstract: A palladium-catalyzed remote 1,n-arylamination (from 1,3- to 1,11-arylamination) of unactivated terminal alkenes with aryl iodides and arylamines has been realized. This three-component reaction proceeded via Pd-catalyzed Heck arylation, alkene isomerization, and aza-Michael addition, exhibiting good… read more here.
Keywords: arylamination; catalyzed remote; unactivated terminal; palladium catalyzed ... See more keywords
Enantioselective hydroamination of unactivated terminal alkenes.
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DOI: 10.2139/ssrn.3936032
Abstract: Asymmetric alkene hydroamination could be a direct route to valuable chiral amines from abundant feedstocks. However, most asymmetric hydroaminations have limited synthetic value because they require a large excess of alkene, occur with modest enantioselectivity,… read more here.
Keywords: terminal alkenes; hydroamination unactivated; enantioselective hydroamination; hydroamination ... See more keywords
Markovnikov-Type Hydrotrifluoromethylchalcogenation of Unactivated Terminal Alkenes with [Me4N][XCF3] (X = S, Se) and TfOH
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DOI: 10.3390/molecules25194535
Abstract: The first Markovnikov-type hydrotrifluoromethylselenolation of unactivated terminal alkenes with the readily accessible [Me4N][SeCF3] reagent and the superacid TfOH is reported. The reaction proceeded at room temperature under catalyst- and additive-free conditions to give the branched… read more here.
Keywords: markovnikov type; tfoh; type hydrotrifluoromethylchalcogenation; unactivated terminal ... See more keywords