Risk‐reducing surgery in unaffected individuals receiving cancer genetic testing in an integrated health care system
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DOI: 10.1002/cncr.34349
Abstract: Germline genetic testing enables primary cancer prevention, including through prophylactic surgery. We examined risk‐reducing surgeries in unaffected individuals tested for hereditary cancer susceptibly between 2010 and 2018 in the Kaiser Permanente Northwest health system. read more here.
Keywords: surgery; risk reducing; genetic testing; cancer ... See more keywords
Predominance of BRCA2 Mutation and Estrogen Receptor Positivity in Unselected Breast Cancer with BRCA1 or BRCA2 Mutation
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DOI: 10.3390/cancers14133266
Abstract: Simple Summary We performed a meataanalysis of BRCA1 or BRCA2 germline pathogenic or likely pathogenic variant (gBRCA) in 108,699 unselected breast cancer patients and in 238,972 unaffected individuals. The metanalysis shows that 3.4% unselected breast… read more here.
Keywords: brca2; unselected breast; breast cancer; cancer ... See more keywords