Impact of BRCA1/2 cascade testing on anxiety, depression, and cancer worry levels among unaffected relatives in a multiethnic Asian cohort
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Genetic Counseling"
DOI: 10.1002/jgc4.1619
Abstract: Cascade testing for families with BRCA pathogenic variants is important to identify relatives who are carriers. These relatives can benefit from appropriate risk management and preventative strategies arising from an inherited increased risk of breast,… read more here.
Keywords: anxiety depression; unaffected relatives; cancer worry; cascade testing ... See more keywords
Neuroanatomical markers of familial risk in adolescents with conduct disorder and their unaffected relatives.
Sign Up to like & getrecommendations! Published in 2021 at "Psychological medicine"
DOI: 10.1017/s0033291721003202
Abstract: BACKGROUND Previous studies have reported brain structure abnormalities in conduct disorder (CD), but it is unclear whether these neuroanatomical alterations mediate the effects of familial (genetic and environmental) risk for CD. We investigated brain structure… read more here.
Keywords: familial risk; unaffected relatives; neuroanatomical markers; risk ... See more keywords
SU72. Abnormal Frontal Synaptic Gain Mediating the P300 in Patients With Psychosis and Their Unaffected Relatives
Sign Up to like & getrecommendations! Published in 2017 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx024.070
Abstract: Abstract Background: The “dysconnection hypothesis” of psychosis suggests that a disruption of functional integration underlies cognitive deficits and clinical symptoms. Impairments in the P300 potential are well documented in psychosis. We investigated intrinsic (self-)connectivity in… read more here.
Keywords: unaffected relatives; patients psychosis; psychosis unaffected; gain ... See more keywords