Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations
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DOI: 10.1093/jac/dkaa187
Abstract: Abstract Background Initial appropriate anti-infective therapy is associated with improved outcomes in patients with severe infections. In critically ill patients, altered pharmacokinetic (PK) behaviour is common and known to influence the achievement of PK/pharmacodynamic targets.… read more here.
Keywords: total unbound; unbound concentrations; ill patients; dosing regimens ... See more keywords