Articles with "uncommon alterations" as a keyword



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EGFR uncommon alterations in advanced non-small cell lung cancer and structural insights into sensitivity to diverse tyrosine kinase inhibitors

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.976731

Abstract: Background: Approximately 10% of patients with non-small cell lung cancer (NSCLC) harbor uncommon epidermal growth factor receptor (EGFR) alterations. This study aims to investigate the therapeutic responses and predict the binding activity of different tyrosine… read more here.

Keywords: non small; cell lung; small cell; activity ... See more keywords