Risk Factors Associated With Antimicrobial Resistance and Adverse Short-Term Health Outcomes Among Adult and Adolescent Female Outpatients With Uncomplicated Urinary Tract Infection.
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DOI: 10.1093/ofid/ofac623
Abstract: Background Increasing antimicrobial resistance makes treating uncomplicated urinary tract infections (uUTIs) difficult. We compared whether adverse short-term outcomes among US female patients were more common when initial antimicrobial therapy did not cover the causative uropathogen.… read more here.
Keywords: urinary tract; uncomplicated urinary; cause; resistance ... See more keywords
The revival of old antibiotics for treatment of uncomplicated urinary tract infections in the era of antibiotic stewardship
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DOI: 10.1097/mou.0000000000000365
Abstract: Purpose of review In the era of increasing antibiotic resistance worldwide, this review highlights the advantages of revival of old antibiotics for treatment of uncomplicated urinary tract infections (uUTIs). Recent findings Recent studies have shown… read more here.
Keywords: uncomplicated urinary; revival old; treatment; treatment uncomplicated ... See more keywords
Dose Selection for Phase III Clinical Evaluation of Gepotidacin (GSK2140944) in the Treatment of Uncomplicated Urinary Tract Infections
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DOI: 10.1128/aac.01492-21
Abstract: Antibiotics are the current standard-of-care treatment for uncomplicated urinary tract infections (uUTIs). However, increasing rates of bacterial antibiotic resistance necessitate novel therapeutic options. ABSTRACT Antibiotics are the current standard-of-care treatment for uncomplicated urinary tract infections… read more here.
Keywords: urinary tract; uncomplicated urinary; tract infections; phase iii ... See more keywords
Treatment patterns, healthcare resource use, and costs associated with uncomplicated urinary tract infection among female patients in the United States
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DOI: 10.1371/journal.pone.0277713
Abstract: Background We evaluated associations between antibiotic prescription and healthcare resource use and costs (Part A), and between antibiotic switching and healthcare resource use, costs, and uncomplicated urinary tract infection recurrence (Part B) in female patients… read more here.
Keywords: urinary tract; uncomplicated urinary; healthcare resource; tract infection ... See more keywords
Whole-Person, Urobiome-Centric Therapy for Uncomplicated Urinary Tract Infection
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DOI: 10.3390/antibiotics11020218
Abstract: A healthy urinary tract contains a variety of microbes resulting in a diverse urobiome. Urobiome dysbiosis, defined as an imbalance in the microbial composition in the microenvironments along the urinary tract, is found in women… read more here.
Keywords: urinary tract; uncomplicated urinary; tract infection; tract ... See more keywords
COSUTI: A Core Outcome Set (COS) for Interventions for the Treatment of Uncomplicated Urinary Tract Infection (UTI) in Adults
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DOI: 10.3390/antibiotics11121846
Abstract: Background: Uncomplicated urinary tract infections (UTIs) are among the most common presentations of bacterial infections in the outpatient setting. The variation of outcomes reported in trials to assess the most effective treatment interventions for uncomplicated… read more here.
Keywords: urinary tract; uncomplicated urinary; interventions treatment; core outcome ... See more keywords