The small molecule inhibitor BX-795 uncouples IL-2 production from inhibition of Th2 inflammation and induces CD4+ T cells resembling iTreg
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DOI: 10.3389/fimmu.2023.1094694
Abstract: Background Treg cells have been shown to be an important part of immune-homeostasis and IL-2 which is produced upon T cell receptor (TCR)-dependent activation of T lymphocytes has been demonstrated to critically participate in Treg… read more here.
Keywords: allergen specific; small molecule; inflammation; uncouples production ... See more keywords