Mitochondrial uncoupling proteins UCP4 and UCP5 from the Pacific white shrimp Litopenaeus vannamei
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-019-09789-5
Abstract: Mitochondrial uncoupling proteins (UCP) transport protons from the intermembrane space to the mitochondrial matrix uncoupling oxidative phosphorylation. In mammals, these proteins have been implicated in several cellular functions ranging from thermoregulation to antioxidant defense. In… read more here.
Keywords: litopenaeus vannamei; shrimp litopenaeus; white shrimp; mitochondrial uncoupling ... See more keywords
Mitochondrial Uncoupling Proteins (UCP1-UCP3) and Adenine Nucleotide Translocase (ANT1) Enhance the Protonophoric Action of 2,4-Dinitrophenol in Mitochondria and Planar Bilayer Membranes
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DOI: 10.3390/biom11081178
Abstract: 2,4-Dinitrophenol (DNP) is a classic uncoupler of oxidative phosphorylation in mitochondria which is still used in “diet pills”, despite its high toxicity and lack of antidotes. DNP increases the proton current through pure lipid membranes,… read more here.
Keywords: adenine nucleotide; uncoupling proteins; nucleotide translocase; dnp ... See more keywords
Unveiling the Role of the Proton Gateway, Uncoupling Proteins (UCPs), in Cancer Cachexia
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DOI: 10.3390/cancers15051407
Abstract: Simple Summary Cancer cachexia is a wasting syndrome mainly driven by chronic inflammation and high energy expenditure. The hyperactivation of the catabolic pathway leads to higher energy utilization by the body. Uncoupling proteins are involved… read more here.
Keywords: role; cancer cachexia; energy; uncoupling proteins ... See more keywords
Uncoupling Proteins as Therapeutic Targets for Neurodegenerative Diseases
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DOI: 10.3390/ijms23105672
Abstract: Most of the major retinal degenerative diseases are associated with significant levels of oxidative stress. One of the major sources contributing to the overall level of stress is the reactive oxygen species (ROS) generated by… read more here.
Keywords: targets neurodegenerative; stress; proteins therapeutic; uncoupling proteins ... See more keywords
Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity
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DOI: 10.3390/metabo12030259
Abstract: Obesity and accompanying type 2 diabetes are among major and increasing worldwide problems that occur fundamentally due to excessive energy intake during its expenditure. Endotherms continuously consume a certain amount of energy to maintain core… read more here.
Keywords: energy; uncoupling proteins; muscle; mice models ... See more keywords