Articles with "uncovering piddosome" as a keyword



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Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation

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Published in 2020 at "Cell Death and Differentiation"

DOI: 10.1038/s41418-020-0556-6

Abstract: The PIDDosome is a multiprotein complex that drives activation of caspase-2, an endopeptidase originally implicated in apoptosis. Yet, unlike other caspases involved in cell death and inflammation, caspase-2 seems to exert additional versatile functions unrelated… read more here.

Keywords: differentiation uncovering; caspase; cellular differentiation; uncovering piddosome ... See more keywords