Articles with "underlie osteosarcomagenesis" as a keyword



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Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants.

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Published in 2023 at "Cancer research"

DOI: 10.1158/0008-5472.can-22-3464

Abstract: Missense mutations in the DNA binding domain of p53 are characterized as structural or contact mutations based on their effect on the conformation of the protein. These mutations show gain-of-function activities, such as promoting increased… read more here.

Keywords: profiles underlie; p53 mutants; underlie osteosarcomagenesis; transcriptional profiles ... See more keywords