Articles with "underlies metformin" as a keyword



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Let-7 underlies metformin-induced inhibition of hepatic glucose production

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2122217119

Abstract: Significance A clear mechanistic understanding of metformin’s antidiabetic effects is lacking. This is because suprapharmacological concentrations of metformin have been used in most studies. Using mouse models and human primary hepatocytes, we show that metformin,… read more here.

Keywords: hepatic glucose; let; let underlies; glucose production ... See more keywords