Understanding of B Cell Receptor Signaling Through a Photo-Activatable Antigen Presentation System.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7474-0_16
Abstract: Antibody responses are initiated by the binding of antigens to cell surface expressed B cell receptors (BCRs) that trigger signaling cascades resulting in the activation of B cells. However, it has been difficult to study… read more here.
Keywords: understanding cell; system; cell receptor; antigen ... See more keywords
Cell Identity Codes: Understanding Cell Identity from Gene Expression Profiles using Deep Neural Networks
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DOI: 10.1038/s41598-019-38798-y
Abstract: Understanding cell identity is an important task in many biomedical areas. Expression patterns of specific marker genes have been used to characterize some limited cell types, but exclusive markers are not available for many cell… read more here.
Keywords: understanding cell; cell types; cell identity; expression ... See more keywords
Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies
Sign Up to like & getrecommendations! Published in 2021 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-002555
Abstract: Rapid advances in immunotherapy have identified adoptive cell transfer as one of the most promising approaches for the treatment of cancers. Large numbers of cancer reactive T lymphocytes can be generated ex vivo from patient… read more here.
Keywords: car cells; cell; chimeric antigen; understanding cell ... See more keywords
Emerging insights and challenges for understanding T cell function through the proteome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1028366
Abstract: T cells rapidly transition from a quiescent state into active proliferation and effector function upon exposure to cognate antigen. These processes are tightly controlled by signal transduction pathways that influence changes in chromatin remodeling, gene… read more here.
Keywords: cell; function; cell function; understanding cell ... See more keywords