Understanding the genetic history of Malay populations in Peninsular Malaysia via KIR genes diversity
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DOI: 10.1002/ajhb.23545
Abstract: Killer cell immunoglobulinâlike receptor (KIR) genes with high polymorphism at genotypic levels are important in providing immune defense and have been expanded towards human population genetics. The aim of this study is to provide supporting… read more here.
Keywords: kir genes; understanding genetic; genetic history; malay ... See more keywords
Understanding the genetic basis of immune responses to fungal infection
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DOI: 10.1080/14787210.2022.2063839
Abstract: ABSTRACT Introduction Fungal infections represent a global public health problem that affects millions of people. Despite remarkable advances achieved over the last decades, available diagnostic and therapeutic tools remain insufficient for the optimal management of… read more here.
Keywords: immune responses; infection; understanding genetic; fungal infection ... See more keywords
Recent advances in our understanding of genetic rhabdomyolysis
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001096
Abstract: Purpose of review This review summarizes recent advances in our understanding of the genetics of rhabdomyolysis. Recent findings Rhabdomyolysis is the acute breakdown of myofibres resulting in systemic changes that can be life-threatening. Environmental triggers,… read more here.
Keywords: rhabdomyolysis; understanding genetic; rhabdomyolysis recent; advances understanding ... See more keywords
Recent Advances in Understanding the Genetic Architecture of Autism.
Sign Up to like & getrecommendations! Published in 2020 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-121219-082309
Abstract: Recent advances in understanding the genetic architecture of autism spectrum disorder have allowed for unprecedented insight into its biological underpinnings. New studies have elucidated the contributions of a variety of forms of genetic variation to… read more here.
Keywords: advances understanding; autism; recent advances; genetic architecture ... See more keywords
Making progress toward understanding the genetic architecture of asthma in the most affected US ethnic group
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/13993003.00329-2017
Abstract: Asthma is a common airway disease that results from complex interactions among genetic and environmental factors. In the USA, asthma disparities by race and ethnicity are a well-known problem [1]: prevalence is highest among Puerto… read more here.
Keywords: genetics; toward understanding; progress toward; making progress ... See more keywords
Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds
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DOI: 10.1186/s12864-017-4004-z
Abstract: BackgroundA better understanding of the genetic architecture underlying complex traits (e.g., the distribution of causal variants and their effects) may aid in the genomic prediction. Here, we hypothesized that the genomic variants of complex traits… read more here.
Keywords: genomic prediction; complex traits; genetic architecture; prediction ... See more keywords
Current Understanding on the Genetic Basis of Key Metabolic Disorders: A Review
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DOI: 10.3390/biology11091308
Abstract: Simple Summary Metabolic disorders (MD) are a challenge to healthcare systems; the emergence of the modern socio-economic system has led to a profound change in lifestyles in terms of dietary habits, exercise regimens, and behavior,… read more here.
Keywords: disease; development; current understanding; understanding genetic ... See more keywords