Recent advances in understanding inherited disorders of keratinization
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DOI: 10.12688/f1000research.14514.1
Abstract: The ichthyoses are a heterogeneous group of skin diseases characterized by localized or generalized scaling or both. Other common manifestations include palmoplantar keratoderma, erythroderma, recurrent infections, and hypohidrosis. Abnormal barrier function is a cardinal feature… read more here.
Keywords: understanding inherited; barrier; inherited disorders; advances understanding ... See more keywords
Current Understanding of Inherited Modifiers of FVIII Pharmacokinetic Variation
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DOI: 10.2147/pgpm.s383221
Abstract: Abstract The inherited bleeding disorder hemophilia A involves the quantitative deficiency of the coagulation cofactor factor VIII (FVIII). Prophylactic treatment of severe hemophilia A patients with FVIII concentrates aims to reduce the frequency of spontaneous… read more here.
Keywords: fviii; fviii pharmacokinetic; modifiers fviii; current understanding ... See more keywords