Mechanistic Understanding of Protein Corona Formation around Nanoparticles: Old Puzzles and New Insights.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202301663
Abstract: Although a wide variety of nanoparticles (NPs) have been engineered for use as disease markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto remained small. A key obstacle in nanomedicine… read more here.
Keywords: corona formation; mechanistic understanding; understanding protein; protein corona ... See more keywords
PlayMolecule Glimpse: Understanding Protein–Ligand Property Predictions with Interpretable Neural Networks
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.1c00691
Abstract: Deep learning has been successfully applied to structure-based protein–ligand affinity prediction, yet the black box nature of these models raises some questions. In a previous study, we presented KDEEP, a convolutional neural network that predicted… read more here.
Keywords: property predictions; glimpse understanding; playmolecule glimpse; understanding protein ... See more keywords
Understanding protein translocation across chloroplast membranes: translocons and motor proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13385
Abstract: Subcellular organelles in eukaryotes are surrounded by lipid membranes. In an endomembrane system, vesicle trafficking is the primary mechanism for the delivery of organellar proteins to specific organelles. However, organellar proteins for chloroplasts, mitochondria, the… read more here.
Keywords: chloroplast; tic complexes; toc tic; understanding protein ... See more keywords