Understanding the Targeting Mechanisms of Multi-Specific Biologics in Immunotherapy with Multiscale Modeling
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101835
Abstract: Summary Immunotherapeutics are frequently associated with adverse side effects due to the elicitation of global immune modulation. To lower the risk of these side effects, recombinant DNA technology is employed to enhance the selectivity of… read more here.
Keywords: understanding targeting; specific biologics; targeting mechanisms; biologics immunotherapy ... See more keywords
Understanding and Targeting Inflammation in Acute Myocardial Infarction: An Elusive Goal.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.05.006
Abstract: O utcomes have improved after acute myocardial infarction (MI) with earlier patient presentation and widespread application of timely reperfusion therapy. However, patients with MI complicated by heart failure, cardiogenic shock, and/or cardiac arrest continue to… read more here.
Keywords: acute myocardial; understanding targeting; myocardial infarction; inflammation ... See more keywords
Understanding and targeting erythroid progenitor cells for effective cancer therapy
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000762
Abstract: Purpose of review It is well described that tumor-directed aberrant myelopoiesis contributes to the generation of various myeloid populations with tumor-promoting properties. A growing number of recent studies have revealed the importance of the previously… read more here.
Keywords: erythroid progenitor; understanding targeting; progenitor cells; tumor ... See more keywords
Abstract SY04-01: Understanding and targeting RNA splicing in breast cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-sy04-01
Abstract: Upregulation of SR proteins, a family of 14 essential splicing factors (SFs), often occurs in solid tumors, including in breast, and promotes mammary cell transformation and metastasis in breast cancer models. SR protein alterations often… read more here.
Keywords: rna splicing; targeting rna; breast; breast cancer ... See more keywords
Editorial: Understanding and targeting neuro-immune interactions within disease and inflammation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1201669
Abstract: COPYRIGHT © 2023 Chang, Carnevale and Chavan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: interactions within; targeting neuro; neuro immune; editorial understanding ... See more keywords