Articles with "understudied orphan" as a keyword



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Constitutive G protein coupling profiles of understudied orphan GPCRs

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Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0247743

Abstract: A large number of GPCRs are potentially valuable drug targets but remain understudied. Many of these lack well-validated activating ligands and are considered “orphan” receptors, and G protein coupling profiles have not been defined for… read more here.

Keywords: protein; coupling profiles; orphan gpcrs; understudied orphan ... See more keywords