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   Articles with "undifferentiated pleomorphic" as a keyword



Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

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recommendations! Published in 2025 at "Molecular Oncology"

DOI: 10.1002/1878-0261.70059

Abstract: Undifferentiated pleomorphic sarcoma (UPS) is a rare cancer with limited systemic treatment options and poor outcomes. To seek novel therapeutic interventions, we undertook mutational analysis of 20 UPS patient tumours, four established UPS cell lines… read more here.

Keywords: led approach; drug; genomics led; undifferentiated pleomorphic ... See more keywords

Prognostic and predictive factors in undifferentiated pleomorphic sarcoma: A long-term study from a large tertiary care urban center.

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recommendations! Published in 2023 at "Journal of surgical oncology"

DOI: 10.1002/jso.27279

Abstract: BACKGROUND AND OBJECTIVES Undifferentiated pleomorphic sarcoma (UPS) is an aggressive type of soft tissue sarcoma (STS) with high rates of metastatic disease and local recurrence. We sought to identify risk factors for local recurrence, metastasis,… read more here.

Keywords: metastasis; sarcoma; local recurrence; recurrence ... See more keywords

Natural history of undifferentiated pleomorphic sarcoma: Experience from the US Sarcoma Collaborative

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recommendations! Published in 2024 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.27620

Abstract: Undifferentiated pleomorphic sarcoma (UPS) is a relatively rare but aggressive neoplasm. We sought to utilize a multi‐institutional US cohort of sarcoma patients to examine predictors of survival and recurrence patterns after resection of UPS. read more here.

Keywords: history; natural history; sarcoma; history undifferentiated ... See more keywords

Spontaneous Undifferentiated Pleomorphic Sarcoma With Mast Cell Infiltration in a Sprague–Dawley Rat: A Case Report

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recommendations! Published in 2025 at "Veterinary Medicine and Science"

DOI: 10.1002/vms3.70242

Abstract: ABSTRACT Undifferentiated pleomorphic sarcomas (UPSs) are tumours of mesenchymal origin typically seen in soft tissues and histologically characterized by pleomorphic tumour cell and multinucleated giant cell (MGC) infiltration. Here, we report UPS in a 23‐month‐old… read more here.

Keywords: dawley rat; sprague dawley; cell; mast ... See more keywords
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UNDIFFERENTIATED PLEOMORPHIC PRIMARY CARDIAC SARCOMAS: A CASE SERIES

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recommendations! Published in 2020 at "Journal of the American College of Cardiology"

DOI: 10.1016/s0735-1097(20)33165-x

Abstract: Primary cardiac sarcomas (PCSs) are extremely rare entities with poor prognosis. We present two patients with undifferentiated pleomorphic sarcoma. (1) 79 year old female with hypertension presented with congestive heart failure. Transthoracic echocardiogram (TTE) and… read more here.

Keywords: undifferentiated pleomorphic; primary cardiac; pleomorphic primary; sarcomas case ... See more keywords
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A RARE CASE OF PRIMARY CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA

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recommendations! Published in 2020 at "Journal of the American College of Cardiology"

DOI: 10.1016/s0735-1097(20)33517-8

Abstract: Primary cardiac malignancies are extremely rare and often have non-specific presentations. Early recognition has significant implications on clinical decision making and prognosis. A 62-year old female with a remote history of esophageal adenocarcinoma treated with… read more here.

Keywords: undifferentiated pleomorphic; rare case; pleomorphic sarcoma; case primary ... See more keywords

210 Molecular Silence in High-Grade Sarcomas: Diagnostic Utility of NGS in Three Cases of Pleomorphic Liposarcoma and Undifferentiated Pleomorphic Sarcoma

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recommendations! Published in 2025 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqaf121.352

Abstract: Pleomorphic liposarcoma (PLS) and undifferentiated pleomorphic sarcoma (UPS) are high-grade sarcomas that remain diagnoses of exclusion, often requiring extensive histologic, immunohistochemical (IHC), and molecular workup. Next-generation sequencing (NGS) is increasingly utilized in soft tissue tumor… read more here.

Keywords: grade sarcomas; high grade; grade; pleomorphic liposarcoma ... See more keywords

Clinical characteristics of undifferentiated pleomorphic sarcoma of bone and the impact of adjuvant chemotherapy on the affected patients: a population-based cohort study.

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recommendations! Published in 2022 at "Japanese journal of clinical oncology"

DOI: 10.1093/jjco/hyac017

Abstract: BACKGROUND Clinical characteristics of undifferentiated pleomorphic sarcoma of bone are not elucidated. Herein, we clarify its clinical features and analyze the efficacy of adjuvant chemotherapy in patients with undifferentiated pleomorphic sarcoma of bone. METHODS Prognostic… read more here.

Keywords: disease specific; undifferentiated pleomorphic; adjuvant chemotherapy; specific survival ... See more keywords
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Mediastinal undifferentiated pleomorphic sarcoma with pleural effusion cytopathologically misdiagnosed as epithelial malignant pleural mesothelioma: An autopsy case report

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recommendations! Published in 2021 at "Thoracic Cancer"

DOI: 10.1111/1759-7714.13898

Abstract: Undifferentiated pleomorphic sarcoma (UPS) is a new disease in the World Health Organization's classification of tumors of soft tissue and bone published in 2013. Primary mediastinal UPS is rare, especially with pleural effusion. Herein, we… read more here.

Keywords: undifferentiated pleomorphic; pleomorphic sarcoma; epithelial malignant; misdiagnosed epithelial ... See more keywords
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Predicting the prognosis of undifferentiated pleomorphic soft tissue sarcoma: a 20‐year experience of 266 cases

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recommendations! Published in 2019 at "ANZ Journal of Surgery"

DOI: 10.1111/ans.15348

Abstract: Undifferentiated pleomorphic sarcoma (UPS) is a rare malignant tumour of mesenchymal origin, which was conceived following re‐classification of malignant fibrous histiocytoma (MFH). The objective of this study is to determine prognostic factors for the outcome… read more here.

Keywords: undifferentiated pleomorphic; tissue sarcoma; soft tissue; predicting prognosis ... See more keywords

EP213 Undifferentiated pleomorphic sarcoma of the breast: presentation of a case

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recommendations! Published in 2019 at "International Journal of Gynecological Cancer"

DOI: 10.1136/ijgc-2019-esgo.275

Abstract: Introduction/Background Undifferentiated pleomorphic sarcoma (UPS) is a malignant mesenchymal neoplasm presenting very rarely as a primary breast tumor. We present a case of UPS of the breast with aggressive clinical behavior. Methodology A 67-year-old patient… read more here.

Keywords: sarcoma; case; pleomorphic sarcoma; tumor ... See more keywords