PP1 Phosphatase Complexes: Undruggable No Longer
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DOI: 10.1016/j.cell.2018.08.007
Abstract: The identification of inhibitors targeting regulatory subunits of serine/threonine PP1 phosphatases reported by Krzyzosiak et al. is a significant step in expanding the pharmacological regulation of phosphorylation beyond kinases. The selective inhibitor of the R15B phosphatase… read more here.
Keywords: phosphatase; pp1 phosphatase; undruggable longer; complexes undruggable ... See more keywords