Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers
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DOI: 10.1158/0008-5472.can-20-3108
Abstract: Effective treatment of pediatric solid tumors has been hampered by the predominance of currently “undruggable” driver transcription factors. Improving outcomes while decreasing the toxicity of treatment necessitates the development of novel agents that can directly… read more here.
Keywords: transcription; undruggable mycn; transcription factor; mycn ... See more keywords