Unexpected severe hepatic and skin toxicities during high dose methotrexate course for osteosarcoma
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DOI: 10.1177/10781552221076456
Abstract: Introduction high dose methotrexate (HD-MTX) regimen is used in osteosarcoma, leukemia and lymphoma treatment. Osteosarcoma is mostly diagnosed in children and adolescents. Most frequent methotrexate toxicities are mucositis, myelosuppression, renal failure, hepatitis and necrotizing encephalopathy.… read more here.
Keywords: dose methotrexate; hepatic skin; skin toxicities; unexpected severe ... See more keywords