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Published in 2025 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.70000
Abstract: A swift microwave‐assisted Mannich cyclization between enaminocarbonitriles, formaldehyde, and primary amines giving 3‐oxothiazolo[3,2‐c]pyrimidine carbonitriles in excellent yields is reported. This protocol has some advantages such as atom‐economy, highly practical, water‐assisted, catalyst‐ and chromatography‐free. Interestingly, some…
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Keywords:
pyrimidine carbonitriles;
synthesis unexpected;
unexpected transformation;
oxothiazolo pyrimidine ... See more keywords