Protein unfolding under isometric tension-what force can integrins generate, and can it unfold FNIII domains?
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2016.12.002
Abstract: Extracellular matrix fibrils of fibronectin (FN) are highly elastic, and are typically stretched three to four times their relaxed length. The mechanism of stretching has been controversial, in particular whether it involves tension-induced unfolding of… read more here.
Keywords: unfold fniii; fniii domains; protein unfolding; force ... See more keywords