Integrated View of Internal Friction in Unfolded Proteins from Single-Molecule FRET, Contact Quenching, Theory, and Simulations
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1722
Abstract: The dynamics of proteins, which are essential for both folding and function, are known to be strongly dependent on solvent viscosity or friction. However, an increasing number of experiments have demonstrated the importance of a… read more here.
Keywords: unfolded proteins; single molecule; friction; internal friction ... See more keywords
Chain Ejection Model for Electrospray Ionization of Unfolded Proteins: Evidence from Atomistic Simulations and Ion Mobility Spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b02926
Abstract: The ion evaporation model (IEM) and the charged residue model (CRM) represent cornerstones of any discussion related to the mechanism of electrospray ionization (ESI). Molecular dynamics (MD) simulations have confirmed that small ions such as… read more here.
Keywords: unfolded proteins; model; cem; chain ejection ... See more keywords
Solid-phase inclusion as a mechanism for regulating unfolded proteins in the mitochondrial matrix
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DOI: 10.1126/sciadv.abc7288
Abstract: Formation of solid-phase protein aggregates in mitochondria is associated with mitochondrial lipid metabolism. Proteostasis declines with age, characterized by the accumulation of unfolded or damaged proteins. Recent studies suggest that proteins constituting pathological inclusions in… read more here.
Keywords: unfolded proteins; solid phase; dump; mitochondrial matrix ... See more keywords
How chloroplasts protect themselves from unfolded proteins
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.51430
Abstract: A genetic screen has identified the first signaling component of the unfolded protein response in chloroplasts. read more here.
Keywords: unfolded proteins; protect unfolded; chloroplasts protect;