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Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2016.55
Abstract: Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and attractive targets for drug discovery. Eukaryotic acetyl-CoA carboxylases are 250 kDa single-chain, multi-domain enzymes and function as dimers and higher oligomers. Their catalytic activity is tightly regulated by…
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Keywords:
unified molecular;
carboxylase;
molecular mechanism;
acetyl coa ... See more keywords