Amphiphilic Arborescent Copolymers and Microgels: From Unimolecular Micelles in a Selective Solvent to the Stable Monolayers of Variable Density and Nanostructure at a Liquid Interface.
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DOI: 10.1021/acsami.7b00772
Abstract: Amphiphilic arborescent block copolymers of two generations (G2 and G3) and polymer microgels, obtained via cross-linking of diblock copolymers, were studied in a selective solvent and at liquid interface via dissipative particle dynamics (DPD) simulations.… read more here.
Keywords: solvent; liquid interface; unimolecular micelles; amphiphilic arborescent ... See more keywords
Systematic Design and Study of Star-like Polymeric Prodrug Unimolecular Micelles β-CD-P[CL-co-(ACL-g-DOX)-SS-MPEG]21 by DPD Simulations
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DOI: 10.1021/acsomega.2c07371
Abstract: Unimolecular micelles composed of a single polymeric molecule have recently attracted significant attention in anti-cancer drug delivery due to their high thermodynamic stability and small particle sizes. Applying the prodrug strategy to unimolecular micelles may… read more here.
Keywords: acl dox; drug; prodrug unimolecular; unimolecular micelles ... See more keywords
Unimolecular Micelles from Randomly Grafted Arborescent Copolymers with Different Core Branching Densities: Encapsulation of Doxorubicin and In Vitro Release Study
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DOI: 10.3390/ma16062461
Abstract: A series of amphiphilic arborescent copolymers of generations G1 and G2 with an arborescent poly(γ-benzyl L-glutamate) (PBG) core and poly(ethylene oxide) (PEO) chain segments in the shell, PBG-g-PEO, were synthesized and evaluated as drug delivery… read more here.
Keywords: branching densities; core; unimolecular micelles; pbg ... See more keywords