Patient-derived antibody recognizes a unique CD43 epitope expressed on all AML and has antileukemia activity in mice.
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DOI: 10.1182/bloodadvances.2017008342
Abstract: Immunotherapy has proven beneficial in many hematologic and nonhematologic malignancies, but immunotherapy for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) is hampered by the lack of tumor-specific targets. We took advantage of the tumor-immunotherapeutic… read more here.
Keywords: antibody; unique cd43; recognizes unique; antibody recognizes ... See more keywords