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Unique, yet Typical Oxyanion Holes in Aspartic Proteases

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Published in 2020 at "ACS Catalysis"

DOI: 10.1021/acscatal.0c03624

Abstract: From studies on pepsin nearly 200 years ago to the modern pursuit of drugs targeting renin, HIV protease, and β-secretases, aspartic proteases continue to shape the understanding of proteins. Thoug... read more here.

Keywords: aspartic proteases; typical oxyanion; oxyanion holes; unique yet ... See more keywords